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See below for our recent publications in peer-reviewed journals, books, and patents. Also, icons to the right filter publications by major topics. Public presentations and lectures can also be downloaded from here.

corresponding/senior author, * equal contribution
For a current list, click here.

Preprints under peer review

Masson H.O., Kuo C.C., Malm M., Lundqvist M., Sievertsson Å, Berling A., Tegel H., Hober S., Uhlén M., Grassi L., Hatton D., Rockberg J.‡, Lewis N.E.Deciphering the determinants of recombinant protein yield across the human secretome, bioRxiv (2022).

Armingol E., Larsen R.O., Cequeira M, Baghdassarian H., Lewis N.E. Unraveling the coordinated dynamics of protein- and metabolite-mediated cell-cell communication. bioRxiv (2022)


169. Baghdassarian H.M.*, Dimitrov D.*, Armingol E.*, Saez-Rodriguez J.‡, Lewis N.E‡. Combining LIANA and Tensor-cell2cell to decipher cell-cell communication across multiple samples. Cell Reports Methods, 4:100758 (2024).

167. Armingol E.‡, Baghdassarian H., Lewis N.E. The diversification of methods for studying cell–cell interactions and communication. Nature Reviews Genetics, in press (2024).

166. Pong A., Mah C.K., Yeo G.W., Lewis N.E. Computational cell-cell interaction technologies drive mechanistic and biomarker discovery in the tumor microenvironment. Current Opinion in Biotechnology, 85:103048 (2024).


159. Aamodt CM, Lewis, NE. Single-cell A/B testing for cell-cell communication, Cell Systems, 14, 428-429 (2023).

157. Baghdassarian H., Blackstone S.A., Clay O.S., Philips R., Matthiasardottir B., Nehrebecky M., Hua V.K., McVicar R., Liu Y., Tucker S.M., Randazzo D., Deuitch N., Rosenzweig S., Mark A., Sasik R., Fisch K.M., Chavan P.P., Eren E., Watts N.R., Gadina M., Schwartz D.M., Sanyal A., Werner G., Murdock D.R., Horita N., Chowdhury S., Dimmock D., Jepsen K., Remmers E.F., Goldbach-Mansky R., Gahl W.A., O’Shea J.J., Milner J.D., Lewis N.E., Chang J., Kastner D.L., Torok K., Oda H., Putnam C.D., Broderick L. Variant STAT4 and Response to Ruxolitinib in an Autoinflammatory Syndrome. New England Journal of Medicine, 388(24):2241-2252 (2023). doi: 10.1056/NEJMoa2202318

156. Ghaddar A., Armingol E., Huynh C., Gevirtzman L., Lewis N.E., Waterston R., O’Rourke E. Whole-body gene expression atlas of an adult metazoan, Science Advances, 9:eadg0506. (2023).

154. Azadiana S., Doustmohammadi A., Naseri M., Khodarahmi M., Arab S.S., Yazdanifar M., Zahiri J.*, Lewis N.E.* Reconstructing the Cell-Cell Interaction Network Among Mouse Immune Cells. Biotechnology & Bioengineering, 120(9), 2756-2764 (2023). doi: 10.1002/bit.28431


146. Armingol E., Ghaddar A., Joshi C.J., Baghdassarian H.M., Shamie I., Chan J., Her H.L., Berhanu S., Dar A., Rodriguez-Armstrong F., Yang O., O’Rourke E.J.‡, Lewis N.E.‡ Inferring the spatial code of cell-cell interactions across a whole animal body. PLoS Computational Biology, 18(11): e1010715 (2022). DOI: 10.1371/journal.pcbi.1010715 (see for cell2cell code)

138. Armingol E.*, Baghdassarian H.*, Martino C., Perez-Lopez A., Aamodt C., Knight R., Lewis N.E. Context-aware deconvolution of cell-cell communication with Tensor-cell2cell. Nature Communications, 13, 3665 (2022). doi: 10.1038/s41467-022-31369-2 , Nature Portfolio Bioengineering (see for more info)


107. Armingol, E.*, Officer, A.*, Harismendy, O.‡, Lewis, N.E.Deciphering cell-cell interactions and communication from gene expression. Nature Reviews Genetics, 22:71–88 (2021). doi: 10.1038/s41576-020-00292-x


95. Saba*, J. A. , Ke*, W. , Yao, C. , Drangowska-Way, A. , Joshi, C., Mony, V.K., Hilzendeger, M., Liu, X., Liu, J., Benjamin, S., Locasale, J., Patti, G., Lewis, N.E.‡, O’Rourke, E.J.‡ Dietary serine enhances chemotherapeutic toxicity in C. elegans through promoting thymidine deficiency in the microbiota. Nature Communications, 11:2587 (2020). doi: 10.1038/s41467-020-16220-w News coverage: UVAToday


69. LaMonte, G., Orjuela-Sanchez, P., Wang, L., Li, S., Swann, J., Cowell, A., Zou, B.Y., Abdel-Haleem, A.M., Villa-Galarce, Z., Moreno, M., Tong-Rios, C., Vinetz, J., Lewis, N.E., Winzeler, E.A. Dual RNAseq shows the human mucosal immunity protein, MUC13, is a hallmark of Plasmodium exoerythrocytic infectionNature Communications, 10:488 (2019). doi: 10.1038/s41467-019-08349-0










7. Bordbar, A., Lewis, N.E., Schellenberger, J., Palsson, B.Ø., Jamshidi, N. Insight into human alveolar macrophage and M. tuberculosis interactions via metabolic reconstructionsMolecular Systems Biology, 6:422 (2010).


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Patents and applications